TrueAllele solves uninterpretable DNA in mother and daughter double homicide

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Using probabilistic genotyping to distinguish family members

B. Pujols, "Using probabilistic genotyping to distinguish family members", Mid-Atlantic Association of Forensic Scientists Annual Meeting, Morgantown, WV, 10-May-2019.


PowerPoint presentation of Mrs. Pujols' talk.

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Interpreting DNA mixtures of family members can be difficult. Probabilistic genotyping (PG) allows scientists to gain more information from their DNA data. The TrueAllele® Casework PG method separates out mixtures into individual genotypes and can then compare to references. These informative genotypes can accurately include or exclude family members. This talk describes a sexual assault case where a mixture sample was resolved to include one brother while excluding the other brother.