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National Institute of Standards and Technology develops DNA mixture standards using Cybergenetics TrueAllele gold standard computing tool
Once a technology has been sufficiently validated, it becomes a useful tool that can perform precise laboratory tasks, such as accurately quantifying the composition of DNA mixtures. Cybergenetics TrueAllele® Casework calculates the DNA mixture weight of each contributor, in addition to inferring genotypes. Dr. Margaret Kline of the National Institute of Standards Technology (NIST) Applied Genetics Group and her colleagues develop the Standard Reference Material (SRM) used by forensic DNA laboratories to calibrate their analytical systems. The NIST standards group now uses TrueAllele as a computing standard to verify the composition of their SRM mixture standards.