Many forensic laboratories are conducting internal validation studies of Cybergenetics TrueAllele® Casework technology. Each group examines particular validation axes. The United States National Institute of Standards and Technology (NIST) Applied Genetics Group is conducting studies on their own TrueAllele system. At the 24th Congress of the International Society for Forensic Genetics (ISFG), Dr. Michael Coble presented his paper with Dr. John Butler on "Exploring the Capabilities of Mixture Interpretation Using TrueAllele Software." Dr. Coble's validation study examined different degrees of allele sharing, two and three contributor mixture ratios, and DNA quantity. Their talk concluded that on DNA mixtures "generally, TrueAllele performs better than RMNE (CPI) and the classic LR with low level contributors."